Second Opinion

What it does

Second Opinion analyzes 2D dental radiographs, including bitewing, periapical, and panoramic images, as they are captured in an existing imaging system. It returns color-coded detections for findings such as incipient and progressed caries, bone loss, calculus, periapical radiolucencies, and restoration margins, with up to 18 findings per image according to Pearl's FAQ. It also offers image quality checks and exportable patient reports with annotated visuals.

Dental practices use it as a second read during diagnosis and as a visual aid when presenting treatment to patients, including comparison views of disease progression. Pearl describes native integration with dental imaging and practice management software, so detections appear inside the existing imaging workflow, and says a standalone web app is also available. Pearl states it holds FDA clearances for intraoral and extraoral radiographs.

It suits dentists, hygienists, and practice managers in clinics or group practices that already view X-rays in a supported imaging system. Access starts with a demo request, and pricing is not published on the product page. It covers 2D radiographs only, compatibility with a specific software version should be confirmed with sales, and accuracy and case-acceptance figures are vendor-reported.

What it can do

• Detects caries, bone loss, calculus, and periapical radiolucencies on 2D radiographs
• Highlights defective restoration margins and existing restorations
• Checks image quality for issues such as underexposure and positioning errors
• Shows comparison views of disease progression
• Exports patient health reports with annotated visuals

Works with

• DEXIS
• Carestream
• Romexis
• Sidexis
• Apteryx XVWeb
• MiPACS
• SOTA Cloud
• Tab32
• Open Dental
• Eaglesoft

Before you choose

• Analyzes 2D radiographs only; 3D imaging is handled by a separate Pearl product.
• Pricing is not published on the product page; confirm cost with Pearl sales.
• Accuracy and case-acceptance statistics are reported by Pearl and its cited studies.

Listed under

• Healthcare
• Caries detection
• Cavity detection
• Clinical decision support
• Dental
• Dental AI
• Dentists

Get started

Demo request form on the product page; compatibility is confirmed with sales.

1. Request a demo from the Second Opinion product page.
2. Confirm your imaging software version is supported with the Pearl sales team.
3. Allow the Pearl team to complete the technical integration, which the FAQ says is typically finished within hours.

Contact Pearl sales for current plans, pricing, and any trial terms.

We couldn’t find published prices for Second Opinion.

Sources for this overview

Product pages, documentation, and pricing checked 29 Oct 2026. Each source supports part of the overview; availability and prices can change.

• Second Opinion - Real-Time Pathology Detection AI for Dentists | Pearl ↗hellopearl.com

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Last checked 29 Oct 2026. Every field keeps its source and date; unknown means we couldn’t confirm it.