UpToDate Expert AI
Generative AI clinical decision support built on UpToDate content
- Tool type
- Clinical generative AI decision support tool
- Made for
- Physicians, clinicians, residents, fellows, and students
- Runs on
- Web and mobile app
- Accessed on the web and through the Expert AI mobile app; requires an internet connection.
What it does
UpToDate Expert AI answers clinical questions in a conversational interface, returning evidence-based recommendations grounded in UpToDate clinical topics. Responses explain the rationale behind each recommendation, highlight key assumptions, and link back to the underlying UpToDate topics so users can trace the sourcing.
Clinicians use it at the point of care for quick answers, differential diagnoses, treatment options, and complex cases. A dedicated mobile app is available for enterprise users, alongside browser access.
It is offered through an UpToDate Pro Plus or trainee subscription in the United States and Canada, and through select UpToDate Enterprise Edition accounts. It requires an internet connection and cannot be used offline. Availability varies by region, and it is considered a clinical decision support tool in some jurisdictions and a reference-only tool in others.
What it can do
- Conversational clinical question answering grounded in UpToDate topics
- Differential diagnosis generation, comparison, and refinement
- Treatment option exploration
- Explanation of assumptions and rationale behind recommendations
- Transparent sourcing that links answers back to UpToDate topics
- Mobile app access for enterprise users
Before you choose
- Requires an internet connection and cannot be used offline.
- Availability varies by region; it is a clinical decision support tool in some jurisdictions and a reference-only tool in others.
- Access depends on an eligible Pro Plus, trainee, or select enterprise subscription.
Listed under
Get started
Request a demo, or subscribe to UpToDate Pro Plus or a trainee subscription where available.
- Confirm eligibility by region and role; Expert AI is available in the United States and Canada through eligible subscriptions.
- Subscribe to UpToDate Pro Plus or a trainee subscription, or sign in through your organization's UpToDate access.
- Use the web interface, or download the Expert AI mobile app if your organization has enterprise access.
Plans and prices
The $219 per year trainee rate is one audience-specific price; Pro Plus and enterprise pricing should be verified at purchase.
- For residents, fellows, and students
- Includes Expert AI access where available
Source: wolterskluwer.com/en/solutions/uptodate/pro/uptodate/uptodate-pro-plus, checked 29 Oct 2026. Prices can change; check before you buy.
Sources for this overview
Product pages, documentation, and pricing checked 29 Oct 2026. Each source supports part of the overview; availability and prices can change.
- AI for Medical Professionals | UpToDate | Wolters Kluwer ↗www.wolterskluwer.com
- UpToDate Pro Plus package featuring GenAI | Wolters Kluwer ↗www.wolterskluwer.com
- UpToDate Mobile App | Wolters Kluwer ↗www.wolterskluwer.com
- UpToDate Training Videos | Wolters Kluwer ↗www.wolterskluwer.com
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Last checked 29 Oct 2026. Every field keeps its source and date; unknown means we couldn’t confirm it.